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A Phase 1a/b Study to Evaluate the Safety and Efficacy of OPB-101, an Autologous Mesothelin (MSLN) CAR T Cell Therapy With Antigen-dependent Expression of OUTSMART™ Designed IL-2 Cytokine in Platinum-resistant Ovarian Cancer

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Trial Profile

A Phase 1a/b Study to Evaluate the Safety and Efficacy of OPB-101, an Autologous Mesothelin (MSLN) CAR T Cell Therapy With Antigen-dependent Expression of OUTSMART™ Designed IL-2 Cytokine in Platinum-resistant Ovarian Cancer

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Jul 2025

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At a glance

  • Drugs OPB 101 (Primary)
  • Indications Ovarian cancer
  • Focus Adverse reactions
  • Sponsors Outpace Bio

Most Recent Events

  • 02 Jul 2025 Status changed from not yet recruiting to recruiting.
  • 27 Jun 2025 New trial record

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