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A Phase 1, Open-Label, Randomized, Crossover, Two-Part Study to Evaluate the Relative Bioavailability of Two ZN-A-1041 Tablet Formulations Compared to Capsule Formulation and the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 Tablet(s) in Healthy Subjects

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Trial Profile

A Phase 1, Open-Label, Randomized, Crossover, Two-Part Study to Evaluate the Relative Bioavailability of Two ZN-A-1041 Tablet Formulations Compared to Capsule Formulation and the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 Tablet(s) in Healthy Subjects

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 12 Aug 2025

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At a glance

  • Drugs Rabeprazole (Primary) ; ZN A 1041 (Primary) ; ZN A 1041 (Primary)
  • Indications HER2 positive breast cancer; Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Genentech

Most Recent Events

  • 15 Jul 2025 New trial record

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