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A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women

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Trial Profile

A Phase 3, Randomized, Active-Controlled, Double-Blind Clinical Study to Evaluate the Efficacy and Safety of MK-8527 Oral Once-Monthly as HIV-1 Preexposure Prophylaxis in Women

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 25 Jul 2025

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At a glance

  • Drugs MK-8527 (Primary) ; Emtricitabine/rilpivirine/tenofovir disoproxil fumarate
  • Indications HIV-1 infections
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Acronyms EXPrESSIVE-10
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 25 Jul 2025 New trial record

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