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Efficacy, Safety, and Tolerability of a GLP-1/GCG Dual Receptor Agonist in Type 2 Diabetes With Early Dementia: A Multicenter, Randomized, Parallel-group, Double-blind, Placebo-controlled Trial

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Trial Profile

Efficacy, Safety, and Tolerability of a GLP-1/GCG Dual Receptor Agonist in Type 2 Diabetes With Early Dementia: A Multicenter, Randomized, Parallel-group, Double-blind, Placebo-controlled Trial

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 25 Nov 2025

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At a glance

  • Drugs Mazdutide (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Adverse reactions
  • Acronyms LIGHT-COG

Most Recent Events

  • 21 Nov 2025 Status changed from not yet recruiting to recruiting.
  • 08 Sep 2025 Planned number of patients changed from 432 to 420.
  • 08 Sep 2025 Planned initiation date changed from 1 Aug 2025 to 1 Oct 2025.

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