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A Phase I/II, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Efficacy of DZD6008 Combined With Sunvozertinib in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations (TIAN-SHAN8)

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Trial Profile

A Phase I/II, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Efficacy of DZD6008 Combined With Sunvozertinib in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations (TIAN-SHAN8)

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 29 Dec 2025

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At a glance

  • Drugs DZD-6008 (Primary) ; Sunvozertinib (Primary) ; Osimertinib
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TIAN-SHAN8
  • Sponsors Dizal Pharmaceutical

Most Recent Events

  • 24 Dec 2025 Status changed from not yet recruiting to recruiting.
  • 05 Aug 2025 New trial record

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