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A Phase 1, Open-Label, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Preliminary Efficacy of Intratumoural Adze1.C in Participants With Metastatic Melanoma

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Trial Profile

A Phase 1, Open-Label, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Preliminary Efficacy of Intratumoural Adze1.C in Participants With Metastatic Melanoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Nov 2025

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At a glance

  • Drugs Adze1 C (Primary)
  • Indications Malignant melanoma
  • Focus Adverse reactions
  • Sponsors Adze Biotechnology

Most Recent Events

  • 21 Nov 2025 Status changed from not yet recruiting to recruiting.
  • 05 Aug 2025 New trial record
  • 11 Jun 2025 According to Adze Biotechnology media release, the company has submitted a Human Research Ethics Committee (HREC) application to Bellberry Limited in Australia for this Phase-1 trial. Following the ethics and regulatory approval, Adze anticipates enrolling patients at clinical sites in Australia later in 2025.

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