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Relative Bioavailability of Two Different Vicadrostat/ Empagliflozin Combinations and Investigation of the Effect of Food on the Pharmacokinetics of a Vicadrostat/ Empagliflozin Combination in Healthy Male and Female Volunteers (an Open-label, Randomised, Single-dose, Three- Way Crossover Study)

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Trial Profile

Relative Bioavailability of Two Different Vicadrostat/ Empagliflozin Combinations and Investigation of the Effect of Food on the Pharmacokinetics of a Vicadrostat/ Empagliflozin Combination in Healthy Male and Female Volunteers (an Open-label, Randomised, Single-dose, Three- Way Crossover Study)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Jan 2026

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At a glance

  • Drugs Empagliflozin (Primary) ; Vicadrostat (Primary)
  • Indications Acute heart failure; Cardiovascular disorders; Chronic heart failure; Decompensated heart failure; Gestational diabetes; Heart failure; Insulin resistance; Kidney disorders; Renal failure; Type 1 diabetes mellitus; Type 2 diabetes mellitus
  • Focus Pharmacokinetics
  • Sponsors Boehringer Ingelheim

Most Recent Events

  • 31 Oct 2025 Status changed from active, no longer recruiting to completed.
  • 16 Oct 2025 Status changed from recruiting to active, no longer recruiting.
  • 19 Sep 2025 Status changed from not yet recruiting to recruiting.

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