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A study to investigate the effect of ASTX660 (tolinapant) on the pharmacokinetics of substrates of OCT1, OCT2, and MATE1 in healthy volunteers

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Trial Profile

A study to investigate the effect of ASTX660 (tolinapant) on the pharmacokinetics of substrates of OCT1, OCT2, and MATE1 in healthy volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 03 Sep 2025

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At a glance

  • Drugs Tolinapant (Primary)
  • Indications Colorectal cancer; Lymphoma; Peripheral T-cell lymphoma; Precursor T-cell lymphoblastic leukaemia-lymphoma; Solid tumours; T-cell lymphoma
  • Focus Pharmacokinetics
  • Sponsors Taiho Oncology

Most Recent Events

  • 03 Sep 2025 New trial record

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