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Phase 2 Study to Assess the Efficacy and Safety of SPY002-072 in Adults With Moderately to Severely Active Rheumatologic Disease

Trial Profile

Phase 2 Study to Assess the Efficacy and Safety of SPY002-072 in Adults With Moderately to Severely Active Rheumatologic Disease

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Aug 2026

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At a glance

  • Drugs SPY 072 (Primary)
  • Indications Axial spondyloarthritis; Plaque psoriasis; Psoriatic arthritis; Rheumatoid arthritis
  • Focus Proof of concept; Therapeutic Use
  • Acronyms SKYWAY-RD
  • Sponsors Spyre Therapeutics

Most Recent Events

  • 05 Aug 2026 According to the Spyre Therapeutics Media Release, company Remain on track for 6 proof-of-concept Phase 2 readouts in 2026, with the rheumatoid arthritis sub-study in SKYWAY.
  • 20 Jul 2026 Planned number of patients changed from 285 to 419.
  • 05 Jun 2026 Status changed from recruiting to active, no longer recruiting.

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