Trial Profile

A Phase 2 Trial Investigating the Addition of Pacritinib to a Hypomethylating Agent as a Bridge to Allogeneic Hematopoietic Stem Cell Transplant in Patients With Accelerated and Blast Phase Myeloproliferative Neoplasms

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 25 Feb 2026

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At a glance

Drugs Azacitidine (Primary) ; Azacitidine (Primary) ; Azacitidine/cedazuridine (Primary) ; Decitabine (Primary) ; Pacritinib (Primary)
Indications Myeloproliferative disorders
Focus Therapeutic Use

20 Feb 2026 Planned initiation date (estimated date of first patient enrollment) changed from 1 Feb 2026 to 15 Mar 2026.
20 Feb 2026 Status changed from not yet recruiting to recruiting.
10 Sep 2025 New trial record

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