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A Phase I/II, First-in-human, Open-label, Dose Escalation and Indication Expansion Study of the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of BNT3212 as Monotherapy or in Combination With BNT327 in Adults With Advanced Solid Tumors

Trial Profile

A Phase I/II, First-in-human, Open-label, Dose Escalation and Indication Expansion Study of the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of BNT3212 as Monotherapy or in Combination With BNT327 in Adults With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 07 Dec 2025

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At a glance

  • Drugs BNT 3212 (Primary) ; Pumitamig (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors BioNTech

Most Recent Events

  • 03 Nov 2025 According to a BioNTech media release, in September the first patient was dosed in this study.
  • 01 Oct 2025 Status changed from not yet recruiting to recruiting.
  • 11 Sep 2025 New trial record

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