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A Single-Dose, Non-Randomised, Open-Label, Parallel-Group Study to Investigate the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Opemalirsen (AZD2373)

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Trial Profile

A Single-Dose, Non-Randomised, Open-Label, Parallel-Group Study to Investigate the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Opemalirsen (AZD2373)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 03 Feb 2026

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At a glance

  • Drugs Opemalirsen (Primary)
  • Indications Kidney disorders
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

Most Recent Events

  • 22 Jan 2026 Planned End Date changed from 26 Dec 2025 to 15 Jun 2026.
  • 22 Jan 2026 Planned primary completion date changed from 26 Dec 2025 to 15 Jun 2026.
  • 10 Oct 2025 Planned End Date changed from 31 Dec 2025 to 26 Dec 2025.

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