Trial Profile

A Single-arm, Open-label Phase 2 Study of Nirogacestat in Adult Japanese Patients With Progressing Desmoid Tumors/Aggressive Fibromatosis (DT/AF)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 23 Sep 2026

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At a glance

Drugs Nirogacestat (Primary)
Indications Fibroma
Focus Therapeutic Use
Sponsors SpringWorks Therapeutics

Most Recent Events

29 Jun 2026 Planned End Date changed from 31 Oct 2029 to 9 Oct 2029.
29 Jun 2026 Planned primary completion date changed from 31 Mar 2027 to 28 May 2027.
06 Apr 2026 Planned End Date changed from 31 Dec 2030 to 31 Oct 2029.

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