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A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Combination With Hydroxyurea or Hydroxyurea/Atezolizumab in Treatment-refractory Solid Tumor Patients

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Trial Profile

A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Combination With Hydroxyurea or Hydroxyurea/Atezolizumab in Treatment-refractory Solid Tumor Patients

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 01 Oct 2025

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At a glance

  • Drugs Atezolizumab (Primary) ; Hydroxycarbamide (Primary) ; OTS 412 (Primary)
  • Indications Biliary cancer; Breast cancer; Colorectal cancer; Gastric cancer; Head and neck cancer; Liver cancer; Malignant melanoma; Renal cell carcinoma; Solid tumours; Urogenital cancer
  • Focus Adverse reactions
  • Sponsors Bionoxx

Most Recent Events

  • 18 Sep 2025 New trial record

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