Trial Profile

An Open Label, Multicenter, Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Profile of M0324, a Bispecific (MUC-1 x CD40) Antibody as Monotherapy, in Combination With Pembrolizumab, and in Combination With Chemotherapy, in Participants With Selected Advanced Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 23 Oct 2025

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At a glance

Drugs Antineoplastics (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Oxaliplatin (Primary) ; Pembrolizumab (Primary)
Indications Adenocarcinoma; Pancreatic ductal carcinoma; Solid tumours
Focus Adverse reactions; First in man
Acronyms TITER
Sponsors EMD Serono Research & Development Institute

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