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A Phase II, Randomized, Double-blind, Placebo-controlled, Multicenter Study Evaluating Efficacy, Safety, and Pharmacokinetics of Crovalimab in Patients With Antiphospholipid Syndrome (APS)

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Trial Profile

A Phase II, Randomized, Double-blind, Placebo-controlled, Multicenter Study Evaluating Efficacy, Safety, and Pharmacokinetics of Crovalimab in Patients With Antiphospholipid Syndrome (APS)

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 06 Mar 2026

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At a glance

  • Drugs Crovalimab (Primary) ; Vitamin K antagonists (Primary)
  • Indications Antiphospholipid syndrome
  • Focus Therapeutic Use
  • Sponsors Roche

Most Recent Events

  • 02 Mar 2026 Status changed from not yet recruiting to withdrawn prior to enrolment. Reason the study was stopped: The study was discontinued due to a strategic business/portfolio decision by the sponsor and was not related to any medical or safety issue.
  • 17 Nov 2025 Planned initiation date changed from 5 Dec 2025 to 16 Mar 2026.
  • 19 Sep 2025 New trial record

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