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A Phase 3 Randomized, Open-label Study of Rinatabart Sesutecan (Rina-S) Versus Treatment of Investigator's Choice (IC) in Patients With Endometrial Cancer After Platinum-Based Chemotherapy and PD(L)-1 Therapy

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Trial Profile

A Phase 3 Randomized, Open-label Study of Rinatabart Sesutecan (Rina-S) Versus Treatment of Investigator's Choice (IC) in Patients With Endometrial Cancer After Platinum-Based Chemotherapy and PD(L)-1 Therapy

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 05 Mar 2026

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At a glance

  • Drugs Rinatabart sesutecan (Primary) ; Doxorubicin; Paclitaxel
  • Indications Carcinoma; Endometrial cancer; Neuroendocrine tumours; Sarcoma
  • Focus Therapeutic Use
  • Acronyms RAINFOL-03
  • Sponsors Genmab

Most Recent Events

  • 09 Dec 2025 Status changed from not yet recruiting to recruiting.
  • 24 Oct 2025 Planned initiation date changed from 15 Oct 2025 to 21 Nov 2025.
  • 19 Sep 2025 New trial record

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