Trial Profile

A Single-Arm, Open-Label Phase 4 Study of Nirogacestat in Adult Premenopausal Females With Desmoid Tumors/Aggressive Fibromatosis (DT/AF)

Status: Recruiting

Phase of Trial: Phase IV

Latest Information Update: 27 May 2026

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At a glance

Drugs Nirogacestat (Primary)
Indications Fibroma
Focus Adverse reactions
Sponsors SpringWorks Therapeutics

Most Recent Events

06 Apr 2026 Planned End Date changed from 30 Mar 2031 to 24 Apr 2031.
06 Apr 2026 Planned primary completion date changed from 28 Feb 2031 to 24 Apr 2031.
22 Sep 2025 New trial record

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