Trial Profile

ITCC-104: HEM-iSMART International Proof of Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory HEMatological Malignancies in Children, Sub-Protocol E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

Status: Not yet recruiting

Phase of Trial: Phase I/II

Latest Information Update: 22 Sep 2025

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At a glance

Drugs Capivasertib (Primary) ; Cytarabine; Dexamethasone; Dexamethasone; Hydrocortisone; Methotrexate; Prednisone; Venetoclax
Indications Haematological malignancies; Precursor cell lymphoblastic leukaemia-lymphoma
Focus Adverse reactions; Proof of concept; Therapeutic Use
Acronyms HEM-iSMART E

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