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Clinical Exploratory Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD)

Trial Profile

Clinical Exploratory Study of YOLT-202 in the Treatment of Alpha-1 Antitrypsin Deficiency (AATD)

Status: Active, no longer recruiting
Phase of Trial: Phase 0

Latest Information Update: 04 Mar 2026

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At a glance

  • Drugs YOLT 202 (Primary)
  • Indications Alpha 1-antitrypsin deficiency
  • Focus Adverse reactions; First in man

Most Recent Events

  • 19 Feb 2026 According to YolTech Therapeutics media release, As of February 6th, two participants genetically confirmed as PiZZ genotype, were enrolled and dosed with YOLT-202 in both the 35 mg and 45 mg dose groups.
  • 19 Feb 2026 Interim Results presented at YolTech Therapeutics media release.
  • 30 Sep 2025 New trial record

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