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A US Phase 3b, Multi-center, Randomized, Double-blind, Double-Dummy Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-Antihistamines

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Trial Profile

A US Phase 3b, Multi-center, Randomized, Double-blind, Double-Dummy Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-Antihistamines

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 02 Nov 2025

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At a glance

  • Drugs Remibrutinib (Primary) ; Dupilumab
  • Indications Chronic urticaria
  • Focus Registrational; Therapeutic Use
  • Acronyms RECLAIM
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 03 Oct 2025 New trial record

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