Trial Profile

Phase II Clinical Trial Evaluating the Safety and Efficacy of Fc-Modified Anti-CD154 mAB (TNX-1500) in Kidney Transplant Recipients

Status: Not yet recruiting

Phase of Trial: Phase II

Latest Information Update: 20 Nov 2025

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At a glance

04 Nov 2025 According to Tonix Pharmaceuticals media release, the study is expected to be initiated in the first half of 2026.
04 Nov 2025 According to Tonix Pharmaceuticals media release, company announced a collaboration with Massachusetts General Hospital (MGH), a founding member of Mass General Brigham (MGB) to conduct a Phase 2 clinical trial evaluating monoclonal antibody (mAb) TNX-1500 in kidney transplant recipients.Study initiation is contingent on institutional review board (IRB) approval and FDA clearance of an investigator-initiated investigational new drug application (IND).
07 Oct 2025 New trial record

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