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A Phase IIIb, Open-label, Multinational Study Assessing the Efficacy and Safety of Dato-DXd Treatment in Patients With HRpositive, HER2 IHC 0, Locally Advanced Inoperable or Metastatic Breast Cancer Refractory to Endocrine Therapy (TROPION-Breast06)

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Trial Profile

A Phase IIIb, Open-label, Multinational Study Assessing the Efficacy and Safety of Dato-DXd Treatment in Patients With HRpositive, HER2 IHC 0, Locally Advanced Inoperable or Metastatic Breast Cancer Refractory to Endocrine Therapy (TROPION-Breast06)

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 07 Oct 2025

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At a glance

  • Drugs Datopotamab deruxtecan (Primary)
  • Indications HER2 negative breast cancer; Male breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms TB06; TROPION-Breast06
  • Sponsors AstraZeneca

Most Recent Events

  • 07 Oct 2025 New trial record

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