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A Phase 2, Randomized, Multicenter, Active-controlled, Double-blind Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of a 2-dose Regimen of Herpes Zoster IN001 mRNA Vaccine (IN001) in Healthy Participants 50 to 79 Years Old

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Trial Profile

A Phase 2, Randomized, Multicenter, Active-controlled, Double-blind Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of a 2-dose Regimen of Herpes Zoster IN001 mRNA Vaccine (IN001) in Healthy Participants 50 to 79 Years Old

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Oct 2025

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At a glance

  • Drugs IN 001 InnoRNA (Primary) ; GSK 137173A
  • Indications Herpes zoster
  • Focus Adverse reactions; Pharmacodynamics; Therapeutic Use
  • Sponsors Shenzhen Shenxin Biotechnology

Most Recent Events

  • 07 Oct 2025 Planned End Date changed from 31 Jan 2028 to 30 Dec 2027.
  • 07 Oct 2025 Planned primary completion date changed from 31 Jan 2028 to 30 Dec 2027.
  • 07 Oct 2025 Planned initiation date changed from 1 Jul 2026 to 1 May 2026.

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