Trial Profile

TulmiSTAR-01: A Two-part, Phase I Dose Escalation and Expansion Followed by a Randomized, Open-label Multicenter, Phase II Study to Assess the Safety and Efficacy of the Combination of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) vs Standard of Care in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 12 Nov 2025

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At a glance

Drugs Luxdegalutamide (Primary) ; Tulmimetostat (Primary) ; Lutetium (177Lu) vipivotide tetraxetan
Indications Adenocarcinoma; Prostate cancer
Focus Adverse reactions; Therapeutic Use
Acronyms TulmiSTAR-01
Sponsors Novartis Pharmaceuticals

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