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A Phase 1, 4-part, Open-label Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult Participants

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Trial Profile

A Phase 1, 4-part, Open-label Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult Participants

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 17 Nov 2025

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At a glance

  • Drugs Trospium chloride/xanomeline (Primary)
  • Indications Alzheimer's disease; Bipolar disorders; Psychiatric disorders; Schizophrenia
  • Focus Pharmacokinetics
  • Sponsors Karuna Therapeutics

Most Recent Events

  • 14 Nov 2025 Status changed from not yet recruiting to recruiting.
  • 07 Oct 2025 New trial record

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