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A Phase 3, Multicenter, Double-Blinded, Randomized Study to Evaluate REGN7508, a Factor XI Monoclonal Antibody, Versus Acetylsalicylic Acid for Prophylaxis of Symptomatic Venous Thromboembolism After Elective Total Knee Arthroplasty (ROXI-ASPEN)

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Trial Profile

A Phase 3, Multicenter, Double-Blinded, Randomized Study to Evaluate REGN7508, a Factor XI Monoclonal Antibody, Versus Acetylsalicylic Acid for Prophylaxis of Symptomatic Venous Thromboembolism After Elective Total Knee Arthroplasty (ROXI-ASPEN)

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 14 Oct 2025

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At a glance

  • Drugs REGN-7508 (Primary)
  • Indications Venous thromboembolism
  • Focus Adverse reactions; Registrational
  • Acronyms ROXI-ASPEN
  • Sponsors Regeneron Pharmaceuticals

Most Recent Events

  • 14 Oct 2025 New trial record

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