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Efficacy of Top-down Therapy With Mirikizumab Versus Standard of Care With Azathioprine in Patients With Newly Diagnosed Moderate-to-severe Ulcerative Colitis: A 52-week, Multicenter, Open-label, Randomized Controlled Trial

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Trial Profile

Efficacy of Top-down Therapy With Mirikizumab Versus Standard of Care With Azathioprine in Patients With Newly Diagnosed Moderate-to-severe Ulcerative Colitis: A 52-week, Multicenter, Open-label, Randomized Controlled Trial

Status: Not yet recruiting
Phase of Trial: Phase IV

Latest Information Update: 25 Nov 2025

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At a glance

  • Drugs Mirikizumab (Primary) ; Mirikizumab (Primary) ; Azathioprine
  • Indications Ulcerative colitis
  • Focus Therapeutic Use
  • Acronyms MIRACLE

Most Recent Events

  • 14 Oct 2025 New trial record

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