Trial Profile

A Safety, Tolerability, Pharmacokinetic, Food Effect, and Proof-of-Concept Study of Single and Multiple Doses of ORX489 in Healthy Adults

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 27 Feb 2026

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At a glance

Drugs ORX 489 (Primary)
Indications Neurodegenerative disorders; Neurological disorders; Psychiatric disorders
Focus Adverse reactions
Sponsors Centessa Pharmaceuticals

Most Recent Events

17 Feb 2026 Status changed from planning to recruiting.
05 Nov 2025 According to Centessa Pharmaceuticals media release, the company is advancing into Advancing in IND-enabling studies;Expect to initiate clinical studies in Q1 2026.
15 Oct 2025 New trial record

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