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A Phase 1/2 Open-label, Multicenter Study of Oral GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Adult Participants With Mismatch Repair-deficient (dMMR) or Microsatellite Instability-High (MSI-H) Solid Tumors

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Trial Profile

A Phase 1/2 Open-label, Multicenter Study of Oral GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Adult Participants With Mismatch Repair-deficient (dMMR) or Microsatellite Instability-High (MSI-H) Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 30 Oct 2025

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At a glance

  • Drugs GSK 5460025 (Primary)
  • Indications Colorectal cancer; Endometrial cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors GSK

Most Recent Events

  • 27 Oct 2025 Status changed from not yet recruiting to recruiting.
  • 16 Oct 2025 New trial record

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