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First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of Intrathecally Administered ALN-SNCA in Participants With Early Parkinson's Disease

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Trial Profile

First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of Intrathecally Administered ALN-SNCA in Participants With Early Parkinson's Disease

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 24 Oct 2025

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At a glance

  • Drugs ALN SNCA (Primary)
  • Indications Parkinson's disease
  • Focus Adverse reactions; First in man
  • Sponsors Regeneron Pharmaceuticals

Most Recent Events

  • 24 Oct 2025 New trial record

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