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A Phase 2 Trial in Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome Undergoing Reduced Intensity or Non-myeloablative Allogeneic Hematopoietic Cell Transplantation With Orca-T

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Trial Profile

A Phase 2 Trial in Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome Undergoing Reduced Intensity or Non-myeloablative Allogeneic Hematopoietic Cell Transplantation With Orca-T

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 04 Nov 2025

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At a glance

  • Drugs Orca-T (Primary)
  • Indications Acute biphenotypic leukaemia; Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Therapeutic Use
  • Acronyms SERENE-T
  • Sponsors Orca Bio

Most Recent Events

  • 28 Oct 2025 Planned primary completion date changed from 1 Oct 2027 to 1 Nov 2027.
  • 28 Oct 2025 Planned initiation date changed from 7 Oct 2025 to 1 Nov 2025.
  • 24 Oct 2025 New trial record

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