Trial Profile

A Phase 3, Randomized, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab With or Without Bevacizumab Compared With Standard of Care as Firstline Maintenance Treatment for Participants With Persistent, Recurrent, or Newly Diagnosed Metastatic Cervical Cancer With PD-L1 CPS Greater Than or Equal to 1 (TroFuse-036/GOG-3123/ENGOT-cx22)

Status: Not yet recruiting

Phase of Trial: Phase III

Latest Information Update: 26 Oct 2025

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At a glance

Drugs Bevacizumab (Primary) ; Carboplatin (Primary) ; Cisplatin (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary) ; Sacituzumab Tirumotecan (Primary)
Indications Adenocarcinoma; Adenosquamous carcinoma; Cervical cancer; Squamous cell cancer
Focus Adverse reactions; Registrational; Therapeutic Use
Acronyms TroFuse-036/GOG-3123/ENGOT-cx22
Sponsors Merck Sharp & Dohme

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