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A Phase 1, Randomized, Placebo-controlled Study With a Double Blind Period With Open-label Extension Period to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ALN-5288 in Adult Patients With Alzheimer's Disease

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Trial Profile

A Phase 1, Randomized, Placebo-controlled Study With a Double Blind Period With Open-label Extension Period to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intrathecally Administered ALN-5288 in Adult Patients With Alzheimer's Disease

Status: Not yet recruiting
Phase of Trial: Phase I

Latest Information Update: 27 Oct 2025

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At a glance

  • Drugs Antidementias (Primary)
  • Indications Alzheimer's disease; Cognition disorders; Dementia
  • Focus Adverse reactions
  • Sponsors Alnylam Pharmaceuticals

Most Recent Events

  • 27 Oct 2025 New trial record

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