A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose (SAD) and Multiple-Ascending-Dose (MAD) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Injection(s) of CLYM116 in Normal Healthy Volunteers
Latest Information Update: 10 Feb 2026
At a glance
- Drugs CLYM 116 (Primary)
- Indications IgA nephropathy
- Focus Adverse reactions; First in man
- Sponsors Climb Bio
Most Recent Events
- 05 Feb 2026 Planned number of patients changed from 58 to 48.
- 09 Jan 2026 Status changed from not yet recruiting to recruiting.
- 08 Jan 2026 According to a Climb Bio media release, the Company achieved FPI and completed dosing of the first cohort in this ongoing Phase 1 clinical trial in healthy volunteers in Dec 2025.