A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose (SAD) and Multiple-Ascending-Dose (MAD) Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Injection(s) of CLYM116 in Normal Healthy Volunteers
Latest Information Update: 28 Nov 2025
At a glance
- Drugs CLYM 116 (Primary)
- Indications IgA nephropathy
- Focus Adverse reactions; First in man
- Sponsors Climb Bio
Most Recent Events
- 25 Nov 2025 Status changed from planning to not yet recruiting.
- 06 Nov 2025 According to a Climb Bio media release, company received regulatory clearance in October 2025 to begin phase 1 trial of CLYM116 in healthy volunteers. The first subject is expected to be dosed by year-end 2025, with initial data anticipated in mid-2026.
- 28 Oct 2025 New trial record