Trial Profile

A randomized, open-label, multicenter Phase 2 trial, evaluating abi-suva in combination with MSD's anti-PD-1 therapy, pembrolizumab (KEYTRUDA) versus pembrolizumab alone as first-line treatment for human papilloma virus (HPV)16-positive, PD-L1-positive recurrent or metastatic head and neck squamous cell carcinoma (1L r/m HNSCC).

Status: Planning

Phase of Trial: Phase II

Latest Information Update: 20 Nov 2025

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At a glance

29 Oct 2025 According to a Nykode Therapeutics media release, Interim analyses for efficacy are planned throughout the trial, with the first expected during 2027.
29 Oct 2025 New trial record

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