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A Randomized Phase III Study of Pirtobrutinib Plus R-CHOP vs. R-CHOP for Participants With Previously Untreated Richter Transformation (PIRAMID)

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Trial Profile

A Randomized Phase III Study of Pirtobrutinib Plus R-CHOP vs. R-CHOP for Participants With Previously Untreated Richter Transformation (PIRAMID)

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 29 Oct 2025

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At a glance

  • Drugs Pirtobrutinib (Primary) ; Cyclophosphamide; Doxorubicin; Hyaluronidase/rituximab; Prednisone; Rituximab; Vincristine
  • Indications Chronic lymphocytic leukaemia; Richter's syndrome
  • Focus Therapeutic Use
  • Acronyms PIRAMID; The PIRAMID Trial

Most Recent Events

  • 29 Oct 2025 New trial record

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