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An Open-Label Study of Mibavademab (REGN4461), a Leptin Receptor Agonist, for the Treatment of Monogenic Obesity Due to Biallelic Loss of Function Variants of the LEP Gene

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Trial Profile

An Open-Label Study of Mibavademab (REGN4461), a Leptin Receptor Agonist, for the Treatment of Monogenic Obesity Due to Biallelic Loss of Function Variants of the LEP Gene

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 29 Oct 2025

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At a glance

  • Drugs Mibavademab (Primary)
  • Indications Obesity
  • Focus Registrational; Therapeutic Use
  • Sponsors Regeneron Pharmaceuticals

Most Recent Events

  • 29 Oct 2025 New trial record

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