Trial Profile

A phase I study of RVU120 with everolimus in children with recurrent or progressive group 3 or 4 medulloblastoma

Status: Planning

Phase of Trial: Phase I

Latest Information Update: 31 Oct 2025

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At a glance

31 Oct 2025 New trial record
18 Sep 2025 According to Ryvu Therapeutics media release, company announced the initiation of a collaboration with the Childrens Memorial Health Institute to explore RVU120 in combination with everolimus in Phase I study.
09 Sep 2025 According to a Ryvu Therapeutics media release, at IPCZD, the study is led by Prof.Bozenna Dembowska-Baginska with the Department of Pediatric Oncology team, in collaboration with Prof.Wieslawa Grajkowska and Prof.Joanna Trubicka. The first drug shipment is expected in Q2 2026, with the MEDWAY project scheduled from July 2025 to June 2033. Company will collaborate closely with the IPCZD team throughout the study.

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