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A phase I study of RVU120 with everolimus in children with recurrent or progressive group 3 or 4 medulloblastoma

Trial Profile

A phase I study of RVU120 with everolimus in children with recurrent or progressive group 3 or 4 medulloblastoma

Status: Planning
Phase of Trial: Phase I

Latest Information Update: 31 Oct 2025

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At a glance

  • Drugs RVU 120 (Primary) ; Everolimus
  • Indications Medulloblastoma
  • Focus Adverse reactions

Most Recent Events

  • 31 Oct 2025 New trial record
  • 09 Sep 2025 According to a Ryvu Therapeutics media release, at IPCZD, the study is led by Prof.Bozenna Dembowska-Baginska with the Department of Pediatric Oncology team, in collaboration with Prof.Wieslawa Grajkowska and Prof.Joanna Trubicka. The first drug shipment is expected in Q2 2026, with the MEDWAY project scheduled from July 2025 to June 2033. Company will collaborate closely with the IPCZD team throughout the study.
  • 09 Sep 2025 According to a Ryvu Therapeutics media release, the company announced its involvement in the MEDWAY project, executed by the Children's Memorial Health Institute (IPCZD), supporting a non-commercial phase I study evaluating RVU120 in combination with everolimus in children with recurrent or progressive Group 3 or 4 medulloblastoma.

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