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A Phase 2, Randomized, Blinded, Placebo-Controlled Trial Investigating the Efficacy and Safety of Visugromab plus Nivolumab with or without Docetaxel versus Docetaxel Monotherapy in Second-Line Treatment of Participants with Metastatic Non-Squamous Non-Small Cell Lung Cancer (GDFATHER-NSCLC-02) - CTL-002-004

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Trial Profile

A Phase 2, Randomized, Blinded, Placebo-Controlled Trial Investigating the Efficacy and Safety of Visugromab plus Nivolumab with or without Docetaxel versus Docetaxel Monotherapy in Second-Line Treatment of Participants with Metastatic Non-Squamous Non-Small Cell Lung Cancer (GDFATHER-NSCLC-02) - CTL-002-004

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 10 Dec 2025

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At a glance

  • Drugs Docetaxel (Primary) ; Nivolumab (Primary) ; Visugromab (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms GDFATHER-NSCLC-02

Most Recent Events

  • 02 Dec 2025 According to CatalYm media release, the company announced that first patient has been dosed.
  • 24 Nov 2025 Planned number of patients changed from 117 to 131.
  • 24 Nov 2025 Status changed from not yet recruiting to recruiting.

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