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A Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SIR4156, a novel NAMPT activator, in healthy adult and elderly participants.

Trial Profile

A Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SIR4156, a novel NAMPT activator, in healthy adult and elderly participants.

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 03 Nov 2025

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At a glance

  • Drugs SIR 4156 (Primary)
  • Indications Musculoskeletal disorders
  • Focus Adverse reactions; First in man
  • Sponsors Sironax Aus Pty

Most Recent Events

  • 03 Nov 2025 New trial record
  • 23 Oct 2025 According to a Sironax media release, the company has three clinical-stage programs and is currently conducting clinical studies with SIR2501, SIR4156, and SIR9900.

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