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A Pivotal, Parallel-Arm, Phase 3, Open-Label, Active-controlled, Global, Multicenter, Randomized Basket Trial Investigating the Efficacy and Safety of Once-weekly Lonapegsomatropin Compared to Daily Somatropin in Prepubertal Children and Adolescents With Growth Failure or Short Stature Due to Growth Hormone Sufficient Disorders - Turner Syndrome, SHOX Deficiency, Small for Gestational Age, and Idiopathic Short Stature

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Trial Profile

A Pivotal, Parallel-Arm, Phase 3, Open-Label, Active-controlled, Global, Multicenter, Randomized Basket Trial Investigating the Efficacy and Safety of Once-weekly Lonapegsomatropin Compared to Daily Somatropin in Prepubertal Children and Adolescents With Growth Failure or Short Stature Due to Growth Hormone Sufficient Disorders - Turner Syndrome, SHOX Deficiency, Small for Gestational Age, and Idiopathic Short Stature

Status: Not yet recruiting
Phase of Trial: Phase III

Latest Information Update: 12 Nov 2025

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At a glance

  • Drugs Lonapegsomatropin (Primary) ; Somatropin
  • Indications Short stature; Somatotropin deficiency; Turner's syndrome
  • Focus Registrational; Therapeutic Use
  • Sponsors Ascendis Pharma

Most Recent Events

  • 04 Nov 2025 New trial record

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