Trial Profile

Phase 1/2 study of LioCyx-M004 in Chronic Hepatitis B patients

Status: Planning

Phase of Trial: Phase I/II

Latest Information Update: 05 Nov 2025

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At a glance

Drugs HBV-specific-TCR-redirected-T-cell-therapy-Lion-TCR (Primary)
Indications Chronic hepatitis; Hepatitis B
Focus Adverse reactions

Most Recent Events

05 Nov 2025 New trial record
14 Sep 2025 According to a Lion TCR media release, has received Investigational New Drug (IND) clearance from the U.S. Food and Drug Administration (FDA) to initiate phase1b/2 clinical trials for its proprietary TCR-T cell therapy, LioCyx-M004, in patients with chronic hepatitis B (CHB).

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