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A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Two Different Formulations of Intravitreal OLN324 in Adult Participants With Either Neovascular (Wet) Age-related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)

Trial Profile

A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Two Different Formulations of Intravitreal OLN324 in Adult Participants With Either Neovascular (Wet) Age-related Macular Degeneration (nAMD) or Diabetic Macular Edema (DME)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 16 Jul 2026

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At a glance

  • Drugs IBI 324 (Primary) ; Faricimab
  • Indications Diabetic macular oedema; Wet age-related macular degeneration
  • Focus Adverse reactions; Proof of concept
  • Acronyms JADE
  • Sponsors Ollin Biosciences

Most Recent Events

  • 13 Jul 2026 According to an Ollin Biosciences media release, results data from JADE study will be presented at the American Society of Retina Specialists (ASRS) 44th Annual Scientific Meeting, taking place from July 15-18 in Montreal, Canada.
  • 13 Jul 2026 Results presented in an Ollin Biosciences media release, company expects final data from the JADE study in March 2026.
  • 13 Jul 2026 Results presented in an Ollin Biosciences Media Release.

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