Trial Profile

Phase 1, 2-Cohort, Open-label, Fixed-sequence, Drug-drug Interaction Study to Evaluate the Effect of Repotrectinib on the Pharmacokinetics of Transporter and CYP P450 Probe Substrates in Healthy Adult Participants

Status: Not yet recruiting

Phase of Trial: Phase I

Latest Information Update: 06 Nov 2025

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At a glance

Drugs Repotrectinib (Primary) ; Bupropion; Digoxin; Flurbiprofen; Metformin; Omeprazole; Rosuvastatin
Indications Adenocarcinoma; CNS cancer; Lymphoma; Multiple myeloma; Non-small cell lung cancer; Solid tumours
Focus Pharmacokinetics
Sponsors Bristol-Myers Squibb

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