Trial Profile

Methotrexate Treatment in Hand Osteoarthritis Refractory to Usual Treatments: A Randomised, Double-blind, Placebo-controlled Trial

Status: Not yet recruiting

Phase of Trial: Phase II/III

Latest Information Update: 03 Apr 2026

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At a glance

Drugs Methotrexate (Primary) ; Folic acid
Indications Osteoarthritis
Focus Therapeutic Use
Acronyms ADEM2 study

Most Recent Events

30 Mar 2026 Planned End Date changed from 31 Dec 2028 to 1 Oct 2027.
30 Mar 2026 Planned initiation date changed from 2 Jan 2026 to 2 May 2026.
07 Nov 2025 New trial record

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