Trial Profile

Study Investigating Tucatinib and Osimertinib Pharmacokinetics in Primary and Metastatic Brain Tumors: the STICK trial

Status: Not yet recruiting

Phase of Trial: Phase I

Latest Information Update: 26 Nov 2025

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At a glance

Drugs Osimertinib (Primary) ; Tucatinib (Primary)
Indications Brain metastases; Breast cancer; Carcinoma; Glioblastoma; Non-small cell lung cancer
Focus Therapeutic Use
Acronyms STICK
Sponsors Amsterdam UMC

Most Recent Events

26 Nov 2025 Planned End Date changed to 1 Oct 2027.
26 Nov 2025 Planned initiation date changed to 1 Oct 2025.
07 Nov 2025 New trial record

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