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A Phase 2, Randomized, Double-Blind, Comparator-Controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of V540A in Healthy Females 16 to 26 Years of Age

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Trial Profile

A Phase 2, Randomized, Double-Blind, Comparator-Controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of V540A in Healthy Females 16 to 26 Years of Age

Status: Not yet recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Jan 2026

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At a glance

  • Drugs V 540 A (Primary) ; V 503
  • Indications Human papillomavirus infections
  • Focus Adverse reactions; Pharmacodynamics
  • Acronyms V540A-005
  • Sponsors Merck Sharp & Dohme

Most Recent Events

  • 24 Dec 2025 Planned End Date changed from 16 Nov 2026 to 4 Apr 2028.
  • 24 Dec 2025 Planned primary completion date changed from 16 Nov 2026 to 4 Apr 2028.
  • 24 Dec 2025 Planned initiation date changed from 5 Dec 2025 to 20 Jul 2026.

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