A Phase 1, First-in-human (FIH), Dose-Escalation and Dose-Optimization Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic Microsatellite Stable (MSS)/Microsatellite Instability Low (MSI-L) Colorectal Cancer
Latest Information Update: 04 Mar 2026
At a glance
- Drugs CBI 1214 (Primary)
- Indications Colorectal cancer
- Focus Adverse reactions; First in man; Pharmacokinetics
Most Recent Events
- 24 Feb 2026 According to Cartography Biosciences media release, Alexander Spira is the principle investigator of the trial.
- 24 Feb 2026 According to Cartography Biosciences media release, the first patient has been dosed in this trial.
- 08 Jan 2026 Status changed from planning to recruiting.